Cetirizine
Cetirizine is a second-generation antihistamine used for hay fever, allergic rhinitis, chronic urticaria (hives), and some allergic skin reactions when your prescriber or pharmacist recommends it. It reduces histamine-driven itching, sneezing, and runny nose.
This medicine is part of the Blood pressure, cholesterol & related category.
Generic name: cetirizine
Quick answers
Short replies to searches people often run before speaking to a clinician. For the overview of what the medicine is used for, see the short summary under the page title above.
What is it for?
Cetirizine is a second-generation antihistamine used for hay fever, allergic rhinitis, chronic urticaria (hives), and some allergic skin reactions when your prescriber or pharmacist recommends it.
How long does it take to work?
Onset varies by condition and dose. Your GP or pharmacist can explain what to expect and when to review.
What are common side effects?
Mild drowsiness, dry mouth, headache, or fatigue.
Can you take paracetamol or ibuprofen with it?
Ask your GP or pharmacist before taking Cetirizine with paracetamol or ibuprofen. Many adults use paracetamol for short periods when appropriate; NSAIDs such as ibuprofen need extra checks with your other medicines and health conditions.
More about what Cetirizine is used for
Cetirizine is a second-generation antihistamine used for hay fever, allergic rhinitis, chronic urticaria (hives), and some allergic skin reactions when your prescriber or pharmacist recommends it.
It reduces histamine-driven itching, sneezing, and runny nose.
How does Cetirizine work, and how long does it take to work?
It blocks H1 receptors peripherally with limited brain entry in many people, so sedation is less than older antihistamines for most.
Some people still feel drowsy — individual variation applies.
How and when should you take Cetirizine?
Often once daily; children’s liquids use age-appropriate dosing on the label.
Swallow tablets with water.
What are the common side effects of Cetirizine?
Mild drowsiness, dry mouth, headache, or fatigue.
Serious side effects of Cetirizine — when to get urgent help
Seek urgent help for severe allergic swelling affecting breathing — antihistamines are adjuncts, not replacements for emergency adrenaline if anaphylaxis is a risk.
What if you miss a dose of Cetirizine?
Take when remembered; if nearly time for next, skip extra.
Who should not take Cetirizine?
Severe kidney failure may need dose reduction. Pregnancy and breastfeeding need pharmacist or GP advice.
Can you take paracetamol or ibuprofen with Cetirizine? — other interactions
Other sedatives add drowsiness. Alcohol can increase sleepiness.
Cetirizine in pregnancy and breastfeeding
Discuss with your prescriber — non-sedating antihistamines are often preferred if treatment is needed.
Blood tests and monitoring on Cetirizine
If symptoms persist despite regular use, review diagnosis with your GP.
What might your GP prescribe instead of Cetirizine?
Loratadine, Fexofenadine, or nasal steroid sprays may be discussed.
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Reviewed by UK registered pharmacists for accuracy and clarity. Content is informational only.
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Frequently asked questions about Cetirizine
People also ask — common Google searches
- What is Cetirizine used for?
- Cetirizine is a second-generation antihistamine used for hay fever, allergic rhinitis, chronic urticaria (hives), and some allergic skin reactions when your prescriber or pharmacist recommends it. It reduces histamine-driven itching, sneezing, and runny nose.
- How long does Cetirizine take to work?
- Onset varies by condition and dose. Your GP or pharmacist can explain what to expect and when to review. Always follow your prescriber’s follow-up plan.
- Can you take Cetirizine with paracetamol or ibuprofen?
- Ask your GP or pharmacist before taking Cetirizine with Paracetamol or Ibuprofen. Many adults use paracetamol for short periods when appropriate; NSAIDs such as ibuprofen need extra checks with your other medicines and health conditions.
- What are the side effects of Cetirizine?
- Mild drowsiness, dry mouth, headache, or fatigue. See the sections below for more detail, including serious side effects and when to seek urgent help.
- Can I drive after cetirizine?
- Most people can, but if you feel sleepy, avoid driving until you know your response.
- Is cetirizine OK every day long term?
- Many people use it through pollen seasons or for chronic urticaria under medical review.
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Often used with
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