DrugABC

UK medicines information — general guidance, not personalised advice.

Diazepam

Diazepam belongs to the benzodiazepine group. In the UK it may be prescribed short term for severe anxiety, muscle spasm, alcohol withdrawal (in supervised settings), or occasionally before some procedures — always as your prescriber directs.

This medicine is part of the Mental health medicines category.

Generic name: diazepam

Quick answers

Short replies to searches people often run before speaking to a clinician. For the overview of what the medicine is used for, see the short summary under the page title above.

  • What is it for?

    Diazepam belongs to the benzodiazepine group.

  • How long does it take to work?

    Many antidepressants need several weeks on a steady dose before full benefit; your GP usually reviews you in that window.

  • What are common side effects?

    Common effects include drowsiness, unsteadiness, poor concentration, and slowed reactions.

  • Can you take paracetamol or ibuprofen with it?

    Ask your GP or pharmacist before taking Diazepam with paracetamol or ibuprofen. Many adults use paracetamol for short periods when appropriate; NSAIDs such as ibuprofen need extra checks with your other medicines and health conditions.

More about what Diazepam is used for

Diazepam belongs to the benzodiazepine group. In the UK it may be prescribed short term for severe anxiety, muscle spasm, alcohol withdrawal (in supervised settings), or occasionally before some procedures — always as your prescriber directs.

Long-term regular use is generally avoided because of dependence, memory, and accident risks.

How does Diazepam work, and how long does it take to work?

It increases the effect of a calming brain chemical (GABA), which reduces anxiety, relaxes muscles, and can cause sleepiness.

Effects begin relatively quickly compared with antidepressants but wear off as the drug leaves the body.

How and when should you take Diazepam?

Take exactly as prescribed — dose and duration are usually kept as short as practical. Swallow tablets with water unless your label says otherwise.

Do not drink alcohol. Do not drive or operate machinery if drowsy.

What are the common side effects of Diazepam?

Common effects include drowsiness, unsteadiness, poor concentration, and slowed reactions. Older adults are more prone to falls and confusion.

Paradoxical agitation occurs rarely.

Serious side effects of Diazepam — when to get urgent help

Seek urgent help for severe breathing difficulty, inability to stay awake, or allergic swelling.

Overdose risk is higher if combined with alcohol, opioids, or other sedatives.

What if you miss a dose of Diazepam?

If you take diazepam regularly and miss a dose, take it when you remember if needed, unless it is nearly time for the next dose. Do not double up.

Many people use it only for short courses — follow the schedule your prescriber gave you.

Who should not take Diazepam?

Not suitable for some people with severe breathing problems, sleep apnoea, severe liver disease, or myasthenia gravis. Caution in pregnancy, especially late pregnancy.

Dependence can develop within weeks — never increase the dose without medical advice.

Can you take paracetamol or ibuprofen with Diazepam? — other interactions

Dangerous sedation with alcohol, opioids, Zopiclone, antihistamines, and many antidepressants. Always check new medicines with a pharmacist.

Diazepam in pregnancy and breastfeeding

Discuss with your GP — use in pregnancy and breastfeeding needs individual risk assessment.

Blood tests and monitoring on Diazepam

Short courses may need little monitoring. If use continues, your prescriber should review need, dose, and withdrawal plan regularly.

What might your GP prescribe instead of Diazepam?

For anxiety, talking therapies, SSRIs, or other non-benzodiazepine options may be preferred longer term. For muscle spasm, physiotherapy or other medicines may be considered.

Reviewed by UK registered pharmacists

Reviewed by UK registered pharmacists for accuracy and clarity. Content is informational only.

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Frequently asked questions about Diazepam

People also ask — common Google searches

What is Diazepam used for?
Diazepam belongs to the benzodiazepine group. In the UK it may be prescribed short term for severe anxiety, muscle spasm, alcohol withdrawal (in supervised settings), or occasionally before some procedures — always as your prescriber directs.
How long does Diazepam take to work?
Many antidepressants need several weeks on a steady dose before full benefit; your GP usually reviews you in that window. Always follow your prescriber’s follow-up plan.
Can you take Diazepam with paracetamol or ibuprofen?
Ask your GP or pharmacist before taking Diazepam with Paracetamol or Ibuprofen. Many adults use paracetamol for short periods when appropriate; NSAIDs such as ibuprofen need extra checks with your other medicines and health conditions.
What are the side effects of Diazepam?
Common effects include drowsiness, unsteadiness, poor concentration, and slowed reactions. Older adults are more prone to falls and confusion. See the sections below for more detail, including serious side effects and when to seek urgent help.
How long can I take diazepam?
Usually the shortest time that helps — often days to a couple of weeks for anxiety. Long-term use increases dependence risk; your GP will review.
Can I drink alcohol with diazepam?
No — the combination can cause dangerous sedation and breathing problems.

Need personalised advice?

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Often used with

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