DrugABC

UK medicines information — general guidance, not personalised advice.

Mirabegron

Mirabegron relaxes the bladder muscle to increase storage capacity, reducing urgency and frequency in overactive bladder when prescribed. It is an alternative to antimuscarinic drugs for some people who cannot tolerate dry mouth or constipation from those medicines.

This medicine is part of the Blood pressure, cholesterol & related category.

Generic name: mirabegron

Quick answers

Short replies to searches people often run before speaking to a clinician. For the overview of what the medicine is used for, see the short summary under the page title above.

  • What is it for?

    Mirabegron relaxes the bladder muscle to increase storage capacity, reducing urgency and frequency in overactive bladder when prescribed.

  • How long does it take to work?

    Blood pressure can fall over days to weeks after starting or changing dose; attend follow-up checks your GP arranges.

  • What are common side effects?

    Increased blood pressure, fast heartbeat, urinary tract infection, headache, or constipation.

  • Can you take paracetamol or ibuprofen with it?

    Ask your GP or pharmacist before taking Mirabegron with paracetamol or ibuprofen. Many adults use paracetamol for short periods when appropriate; NSAIDs such as ibuprofen need extra checks with your other medicines and health conditions.

More about what Mirabegron is used for

Mirabegron relaxes the bladder muscle to increase storage capacity, reducing urgency and frequency in overactive bladder when prescribed.

It is an alternative to antimuscarinic drugs for some people who cannot tolerate dry mouth or constipation from those medicines.

How does Mirabegron work, and how long does it take to work?

Selective beta-3 adrenergic stimulation promotes bladder relaxation without the airway effects seen with older non-selective beta agonists at standard doses.

Blood pressure can rise slightly.

How and when should you take Mirabegron?

Usually once daily; modified-release tablets are swallowed whole with water.

Kidney or liver impairment may need dose limits.

What are the common side effects of Mirabegron?

Increased blood pressure, fast heartbeat, urinary tract infection, headache, or constipation.

Serious side effects of Mirabegron — when to get urgent help

Seek help for severe hypertension symptoms, palpitations with fainting, or allergic swelling.

What if you miss a dose of Mirabegron?

Take when remembered unless nearly time for next; do not double.

Who should not take Mirabegron?

Severe uncontrolled hypertension in some summaries, end-stage kidney disease on dialysis for some brands — check your leaflet.

Can you take paracetamol or ibuprofen with Mirabegron? — other interactions

Metoprolol and desipramine levels can be affected; other drugs using the same liver enzymes need pharmacist review.

Mirabegron in pregnancy and breastfeeding

Discuss with your prescriber before use.

Blood tests and monitoring on Mirabegron

Blood pressure after starting; symptom diaries for bladder function.

What might your GP prescribe instead of Mirabegron?

Oxybutynin, solifenacin, tolterodine, or bladder botulinum toxin in specialist care.

Reviewed by UK registered pharmacists

Reviewed by UK registered pharmacists for accuracy and clarity. Content is informational only.

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Frequently asked questions about Mirabegron

People also ask — common Google searches

What is Mirabegron used for?
Mirabegron relaxes the bladder muscle to increase storage capacity, reducing urgency and frequency in overactive bladder when prescribed. It is an alternative to antimuscarinic drugs for some people who cannot tolerate dry mouth or constipation from those medicines.
How long does Mirabegron take to work?
Blood pressure can fall over days to weeks after starting or changing dose; attend follow-up checks your GP arranges. Always follow your prescriber’s follow-up plan.
Can you take Mirabegron with paracetamol or ibuprofen?
Ask your GP or pharmacist before taking Mirabegron with Paracetamol or Ibuprofen. Many adults use paracetamol for short periods when appropriate; NSAIDs such as ibuprofen need extra checks with your other medicines and health conditions.
What are the side effects of Mirabegron?
Increased blood pressure, fast heartbeat, urinary tract infection, headache, or constipation. See the sections below for more detail, including serious side effects and when to seek urgent help.
Mirabegron vs oxybutynin — which is better?
Mirabegron avoids some anticholinergic side effects but can affect blood pressure — your prescriber matches the drug to your health profile.
Can mirabegron cause palpitations?
Increased heart rate is possible — report sustained palpitations to your GP.

Need personalised advice?

Your local pharmacist or GP surgery can help with questions about your medicines, side effects, and alternatives that may be suitable for you.

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Often used with

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